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In this Review, we discuss the chemistry of next generation gold drugs, which encompasses oxidation states, geometry, ligands, coordination, and organometallic compounds for infectious diseases, cancer, inflammation, and as tools for chemical biology via gold–protein interactions
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Interestingly, we found that the protein expression levels of HO-1 in β-glucan + LPS treatment groups were obviously higher than those of LPS treatment group, while such increased trend was evidently inhibited by either laminarin or ML385, implying that HO-1 could be a downstream target of Dectin-1/Nrf2 signaling pathway